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| Director: | 
James Gunn |  | 
Writer: | 
James Gunn |  | 
Starring: | 
Nathan Fillion, Gregg Henry, Michael Rooker, Elizabeth Banks |  | 
Released: | 
May 18, 2006 |  | 
Rating: | 
 
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Runtime: | 
96 minutes
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Websites: | 
 
 
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Story: | 
As Slither begins, we are introduced to one of the few leaders of Wheelsy's pack -- successful, 
albeit oafish, local businessman Grant Grant. With beautiful young wife Starla, a large house 
and fat bank account, Grant truly relishes his 'big fish-small pond' role in the town. Other than 
the fact that the passionate love he feels for his woman goes completely unrequited, he's a man 
content. But things are about to change for Grant in ways no one could have ever imagined.
  
On a humdrum evening, Grant hits the local honky-tonk for an all-night bender. There he encounters 
Brenda Gutierrez, the younger sister of an old girlfriend, who's more than willing to listen to 
Grant's woes. Abandoning their drinks for a moonlight stroll, the pair discovers something slimy 
in the woods behind the bar. Near the remains of what appears to be a meteor, Grant and Brenda find 
a trail of glistening, noxious ooze and a pulsating, unidentifiable mass. Suddenly, the glob comes 
to life and overtakes Grant, penetrating his body with a pustule-covered tentacle. An alien parasite 
has found and infected its unlucky human host, an unwilling transporter who now must continue to 
infect others in order to survive.
  
Signs of Grant's transformation are instantly apparent: the extended periods of time he spends in 
his basement amassing meat products; the strange sounds and odors Starla notices emanating from the 
bowels of their home; his erratic behavior towards his wife -- sometimes loving and tender, then 
suddenly ferocious and aggressive. And most gruesomely, the denizens begin to suspect Grant's 
involvement in an unusual number of missing pets and farm animals around town.
  
With each day that passes, Grant becomes less and less human, evolving into a bloodthirsty creature 
driven by a primal need to kill and destroy the uninfected. Unfortunately, Grant's not the only 
problem. He has begun spawning scores of giant slugs that are out to inoculate any redneck into 
whom they can get their siphons.
  
Now joining Starla on her quest to stop Grant and the infected is her former high school beau, 
local Chief of Police Bill Pardy. A handsome everyman with a burning love for Starla, Pardy gets 
suspicious of his old rival and leads the charge to take him down. The pair gathers a makeshift 
crew of uninfected, including foul-mouthed Mayor Jack MacReady and smart-ass teen beauty Kylie 
Strutemyer to help stop the evil plague laying siege to Wheelsy.
  
As the rebels attempt to avoid both the slippery slugs that just want to worm inside of them and 
their former neighbors-turned-meat-eating zombies, it's anyone's guess as to who will stay slug-free. 
But when the ragtag team comes face-to-face with an ancient, vengeful entity beyond all human 
comprehension, fierce alliances will be forged, former friends will be destroyed and a hilariously 
gruesome showdown will take place -- hillbilly style.
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Cast: | 
| 
Nathan Fillion
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Bill Pardy |  | 
Elizabeth Banks
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Starla Grant |  | 
Gregg Henry
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Jack MacReady |  | 
Michael Rooker
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Grant Grant |  | 
Don Thompson
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Wally |  | 
Xantha Radley
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Uptight Mom |  | 
Tania Saulnier
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Kylie Strutemyer |  | 
Dustin Milligan
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Drawing Boy |  | 
Haig Sutherland
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Trevor |  | 
Jennifer Copping
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Margaret |  | 
Zak Ludwig
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Gina Kid |  | 
Kathryn Kirkpatrick
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Karaoke Woman |  | 
Brenda James
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Brenda Gutierrez |  | 
Lorena Gale
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Janene |  | 
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